Susceptibility of tissue cultures of canine origin to viruses. LF-26.

The suitability of tissue cultures of canine origin for isolation of viruses from dogs was studied. Primary cultures of kidney, lung, heart and whole dog embryo, low-passage tracheal cells and a continuous line of epithelial-like cells derived from dog kidney were challenged with 27viruses. These included the infectious caninehepatitis virus, two coxsackieAand six coxsackieBviruses, three types of poliovirus, ten ECHO viruses, one adenovirus, the western and eastern strains of equine encephalitis virus, and A and B strains of influenza virus. Although each type of cells supported the growth of one or more viruses as evidenced by the cytopathic effect none of them appeared to be more suitable for virus isolation studies than HeLa and monkey kidney cells.